Ishtiaq Khaliq
Gene Therapy Molecular Biology Sciences Lead UCB
Seminars
Wednesday 6th May 2026
Roundtable Discussion: Comparing Long-Read Versus Short-Read Sequencing to Resolve the Identity – Integrity Confusion in Vector Analytics
1:45 pm
10-minute presentation followed by 30-minute roundtable discussion
- Case example of where identity looked near ‘perfect’ but was not indicative of strong potency
- Limitations of long-read sequencing and how they affect QC readiness
- Why NGS results frequently disagree with AUC, ddPCR, and functional potency assays
- How emerging automation/algorithms are improving reproducibility
