Fabien Dorange

Company: SparingVision
Job title: Director Analytical Sciences
Seminars:
The Need for an Unbiased Assay to Detect and Quantify Replication Competent AAV in Clinical Vector Products 4:00 pm
Replication-competent AAVs (rcAAV) are gene therapy product-related impurities that could have associated safety risks for patients. Our data show that the cell-based method can result in significantly different results between testing facilities using different assay protocols. Moreover, we show that positive or negative results are highly dependent on the capacity of serotypes to infect the…Read more
day: Day One