Fabien Dorange

Fabien Dorange

Company: SparingVision

Job title: Director Analytical Sciences

Seminars:

The Need for an Unbiased Assay to Detect and Quantify Replication Competent AAV in Clinical Vector Products 4:00 pm

Replication-competent AAVs (rcAAV) are gene therapy product-related impurities that could have associated safety risks for patients. Our data show that the cell-based method can result in significantly different results between testing facilities using different assay protocols. Moreover, we show that positive or negative results are highly dependent on the capacity of serotypes to infect the…Read more

day: Day One

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