David Dobnik

Company: National Institute of Biology

Job title: Senior Research Associate

Seminars:

Confronting the Challenges of Viral Vector Genome Integrity for Consistent Gene Therapy Outcomes 4:30 pm

Understanding accurate detection of viral vector genome integrity is crucial to ensure the vector carries the correct genetic material without mutations, deletions, or rearrangements that could impact therapeutic efficacy or safety Address how variability in the efficiency of viral packaging and transduction processes can lead to inconsistencies in genome integrity, requiring robust methods to quantify…Read more

day: Day One

Choosing Between qPCR vs. dPCR vs. ddPCR for Robust Analytics & Regulatory Compliance 9:00 am

In gene therapy development, accurate quantification of viral vectors is critical for assessing potency and ensuring therapeutic efficacy. This discussion will explore the strengths and limitations of qPCR, dPCR, and ddPCR, and how selecting the right method impacts early versus late-stage gene therapy processes. PCR Method Comparison Pros & Cons: Overview of qPCR, dPCR, and…Read more

day: Pre-Conference QC Readiness Track B - AM