(NEW DATA) Utilising HPLC for Analysis of Aggregation & to Enhance Separation Resolution Between Empty, Full & Partial Capsids
Time: 12:00 pm
day: Day Two Track B AM
Details:
- Refining HPLC to enable quantification of critical CQAs including aggregation and empty-full ratio
- Presenting data establishing robust separation resolution between full and empty particles
- Understanding mechanisms for validating contemporary HPLC techniques across AAV products
- Benchmarking HPLC to cryo-EM and ddPCR-ELISA to demonstrate reduced variability
