Ricardo Gomes
Senior Research Associate IBET - Instituto de Biologia Experimental e Tecnologica
Seminars
Wednesday 6th May 2026
Improving Gene Therapy Safety with High-Sensitivity Impurity Profiling that Identifies Hidden Contaminants Across the Process
3:30 pm
- Pinpointing where HCPs, residual DNA, and process-related contaminants accumulate across upstream, downstream, and final formulation to give teams a proactive risk profile
- Evaluating when LC-MS, DIA-MS, ddPCR and immunoassays complement each other to ensure no single assay misses critical contaminants
- Linking impurity patterns to potency drift, vector quality, and safety signals
