Roundtable Discussion: Comparing Long-Read Versus Short-Read Sequencing to Resolve the Identity – Integrity Confusion in Vector Analytics
10-minute presentation followed by 30-minute roundtable discussion
- Case example of where identity looked near ‘perfect’ but was not indicative of strong potency
- Limitations of long-read sequencing and how they affect QC readiness
- Why NGS results frequently disagree with AUC, ddPCR, and functional potency assays
- How emerging automation/algorithms are improving reproducibility