Damon Barbacci

Damon Barbacci

Company: Spark Therapeutics

Job title: Analytical Development Lead


(CASE STUDY) Mass Spectrometric VP Characterisation of rAAV Gene Therapy Products 2:00 pm

Intro to our LCMS approach for Intact mass, peptide mapping, and PTM profiling Example of minor VP protein ID using combination of LC-MS and CE-SDS Example of PTM profiling to support formulation selectionRead more

day: Day Two PM

Preparing for Late-Stage Extended Characterisation 9:00 am

Extended characterisation is a pivitol piece of the analytical toolbox needed to take a product through late phase development into approval. Yet with only a handfull of approvals on the market thus little to base experience from and regulatory guidelines trying to catch up with the understanding of a hugely complex product, there is still…Read more

day: Pre-Conference Day Track B

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